CRP is an acute phase protein synthesized in the liver. It consists of five identical subunits and belongs to the family of pentraxins. During inflammatory processes an increase in CRP concentration can be detected within 4-6 hours with a peak concentration within 48 hours and a return to normal levels within 1-2 weeks. With this fast response CRP is used in the diagnosis and treatment of inflammatory diseases in dogs.
The Gentian canine CRP is an in vitro diagnostic test for the quantitative determination of Canine CRP in dog serum. The assay is based on Gentian’s Nanosense Technology. This technology allows developing a fast, robust and reproducible assay which can be easily adapted to a variety of clinical chemistry platforms allowing veterinary labs to include this important analyte into the routine test panel in an efficient way.
Serum or plasma sample from dog is mixed with anti-canine CRP immunoparticles. Canine CRP from the sample and anti-canine CRP from the immunoparticles aggregates. The complex particles created absorb light, and by turbidimetry the absorption is related to canine CRP concentration in the sample via interpolation on an established standard calibration curve.
Gentian Canine CRP internal calibration adjusted against a commercially available human CRP assay used for Canine CRP determination at the Swedish University of Agriculture Sciences Animal Hospital. No international standard is available for canine CRP.
|Gentian Canine CRP Reagent kit
|Gentian Canine CRP Calibrator kit (6 levels), 0.5 ml||REF 1551|
|Gentian Canine CRP Control kit (2 levels), 0.5 ml||REF 1519|
|Format||2 reagents, ready to use|
|Sample material||Serum, Plasma|
|Time to result||5 minutes*|
|Range||10 – 300 mg/L|
|Security zone||up to 1000mg/L|
|Stability of calibration||4 weeks|
|Protocols||Abbott Architect c4000, Olympus AU400, Pentra, Global|
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